Alex Perlmutter

Alex Perlmutter

Observational Research Manager

Amgen

Biography

I am an accomplished epidemiologist, who specializes in the principled use and development of advanced causal inference methods for answering pharmacepideiological research questions in numerous therapeutic areas. In the real-world evidence space, I have designed and conducted dermatology and oncology studies, the latter being those on high-risk non-muscle invasive bladder and advanced non-small cell lung cancer. I am currently an Observational Research Manager at Amgen contributing to studies that shape the benefit/risk profile of our bone products. I received an MPH and a PhD in Epidemiology from Columbia University Mailman School of Public Health where I had formal training epidemiological methods with a primary focus on causal inference methods.

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Interests
  • Linking claims and clinical data
  • Causal inference methods in pharmacepidemiology
  • Osteoporosis and bone pharmacoepidemiology
Education
  • PhD in Epidemiology, 2023

    Columbia University

  • MPH in Epidemiology, 2016

    Columbia University

  • BA in Business communications, 2010

    Richmond University

Skills

R
Study design
Data viz

Experience

 
 
 
 
 
Amgen
Observational Research Manager
Jul 2022 – Present Thousand Oaks, CA (remote in NY)

Responsibilities include:

  • Contributing to studies addressing the benefit/risk profile of bone products
 
 
 
 
 
Target RWE
Senior epidemiologist
Jul 2022 – Present Durham, NC (remote in NY)

Responsibilities include:

  • Designing pharmacoepidemiological hepatology, dermatology, and oncology studies with claims and electronic health record data, including studies that integrate both types of data
  • Implementing advanced causal inference methods to surmount common problems in pharmacoepidemiological analyses
    • Clone censor weight approach to address immortal time bias due to the start of follow-up and treatment initiation not coinciding
    • Inverse probability of censoring weight approach for informative right censoring
    • Prevalent new user design for non-contemporaneous marketing in comparative effectiveness studies
  • Writing proposals and developing presentations to help Target RWE win new contracts and continue existing ones
 
 
 
 
 
Columbia University
Doctoral candidate
Aug 2017 – Mar 2023 New York, NY
  • Completed doctoral epidemiology training and dissertation on nicotine vaping’s unintended consequences
  • Performed teaching assistant duties for numerous epidemiology and statistics courses

Apps

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My dissertation Shiny apps

Recent Publications

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(2023). Associations between relative deprivation with opioid use among working-age adults during the great recession. Journal of Psychiatric Research.

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(2022). SER 2022 Poster. In SER.

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(2021). The Association of Pain Levels and Low Physical Activity among Older Women. Geriatrics.

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(2020). Identification of patient perceptions that can affect the uptake of interventions using biometric monitoring devices: systematic review of randomized controlled trials. Journal of medical Internet research.

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(2019). Correct knowledge of medical cannabis legal status in one's own state: Differences between adolescents and adults in the United States, 2004--2013. Addictive behaviors.

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(2019). Sex differences in nonmedical prescription tranquilizer and stimulant use trends among secondary school students in Argentina, Chile, and Uruguay. Drug and alcohol dependence.

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(2018). Nonmedical prescription drug use among adolescents: global epidemiological evidence for prevention, assessment, diagnosis, and treatment. Current addiction reports.

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(2018). Nonmedical prescription drug use in adolescents and young adults. The prescription drug abuse epidemic: Incidence, treatment, prevention, and policy.

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(2017). Is employment status in adults over 25 years old associated with nonmedical prescription opioid and stimulant use?. Social psychiatry and psychiatric epidemiology.

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(2017). Prescription opioid use disorder and heroin use among youth nonmedical prescription opioid users from 2002 to 2014. Addictive behaviors.

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